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  • 产品名称：PP2A-gamma Positive Control for STJ505958 peptide (STJ505737)

  • 产品型号：STJ505737-5
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
PP2A-gamma Positive Control for STJ505958 peptide (STJ505737)
详情介绍：
Applications: WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: PP2A-gamma Positive Control for STJ505958 is synthetically produced from the sequence and is suitable for use in western blot applications.
Formulation: Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: PPP2R5C
Gene ID: 5527
Uniprot ID: 2A5G_HUMAN
Specificity: This is positive control is recommended for use in combination with PP2A-gamma antibody STJ505958.
Immunogen: Purified Serine/Threonine-Protein Phosphatase 2A B56 Gamma1 subunit.
Post Translational Modifications Isoform Gamma-3 is phosphorylated on serine residues. Isoform Gamma-1 phosphorylation by ERK2 is IER3-dependent and inhibits ERK dephosphorylation by PP2A-PPP2R5C.
Function The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. The PP2A-PPP2R5C holoenzyme may specifically dephosphorylate and activate TP53 and play a role in DNA damage-induced inhibition of cell proliferation. PP2A-PPP2R5C may also regulate the ERK signaling pathway through ERK dephosphorylation.
Peptide Name Serine/Threonine-Protein Phosphatase 2a 56 Kda Regulatory Subunit Gamma Isoform
Pp2a B Subunit Isoform B'-Gamma
Pp2a B Subunit Isoform B56-Gamma
Pp2a B Subunit Isoform Pr61-Gamma
Pp2a B Subunit Isoform R5-Gamma
Renal Carcinoma Antigen Ny-Ren-29
Database Links Reactome: R-HSA-141444
Reactome: R-HSA-195253
Reactome: R-HSA-196299
Reactome: R-HSA-2467813
Reactome: R-HSA-2500257
Reactome: R-HSA-389513
Reactome: R-HSA-432142
Reactome: R-HSA-4641262
Reactome: R-HSA-5339716
Reactome: R-HSA-5358747
Reactome: R-HSA-5358749
Reactome: R-HSA-5358751
Reactome: R-HSA-5358752
Reactome: R-HSA-5467337
Reactome: R-HSA-5467340
Reactome: R-HSA-5467348
Reactome: R-HSA-5663220
Reactome: R-HSA-5673000
Reactome: R-HSA-5675221
Reactome: R-HSA-6804757
Reactome: R-HSA-6811558
Reactome: R-HSA-68877
Reactome: R-HSA-9648025
Cellular Localisation Nucleus
Chromosome
Centromere
Alternative Peptide Names Serine/Threonine-Protein Phosphatase 2a 56 Kda Regulatory Subunit Gamma Isoform protein
Pp2a B Subunit Isoform B'-Gamma protein
Pp2a B Subunit Isoform B56-Gamma protein
Pp2a B Subunit Isoform Pr61-Gamma protein
Pp2a B Subunit Isoform R5-Gamma protein
Renal Carcinoma Antigen Ny-Ren-29 protein
PPP2R5C protein
KIAA0044 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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