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  • 产品名称：Mouse ALCAM/CD166 protein (Recombinant) (C-His & Avi) {Biotin} (STJP002410)

  • 产品型号：STJP002410-100
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Mouse ALCAM/CD166 protein (Recombinant) (C-His & Avi) {Biotin} (STJP002410)
详情介绍：
Host: HEK293 cells
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Mouse ALCAM/CD166-C-His & Avi protein was developed from hek293 cells and has a target region of C-His & Avi. For use in research applications.
Conjugation: Biotin
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Endotoxin: Less than 1EU per Mu g by the LAL method.
Gene Symbol: Alcam
Gene ID: 11658
Uniprot ID: CD166_MOUSE
Immunogen Region: Tyr28-Lys527
Immunogen: Recombinant Biotinylated Mouse ALCAM/CD166 Protein is expressed from Expi293 with His tag and Avi tag at the C-terminal.；It contains Tyr28-Lys527.
Post Translational Modifications Glycosylated.
Function Cell adhesion molecule that mediates both heterotypic cell-cell contacts via its interaction with CD6, as well as homotypic cell-cell contacts. Promotes T-cell activation and proliferation via its interactions with CD6. Contributes to the formation and maturation of the immunological synapse via its interactions with CD6. Mediates homotypic interactions with cells that express ALCAM. Mediates attachment of dendritic cells onto endothelial cells via homotypic interaction. Inhibits endothelial cell migration and promotes endothelial tube formation via homotypic interactions. Required for normal organization of the lymph vessel network. Required for normal hematopoietic stem cell engraftment in the bone marrow. Plays a role in hematopoiesis.required for normal numbers of hematopoietic stem cells in bone marrow. Promotes in vitro osteoblast proliferation and differentiation. Promotes neurite extension, axon growth and axon guidance.axons grow preferentially on surfaces that contain ALCAM. Mediates outgrowth and pathfinding for retinal ganglion cell axons.
Protein Name Cd166 Antigen
Activated Leukocyte Cell Adhesion Molecule
Ben
Protein Dm-Grasp
Cd Antigen Cd166
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Cell Projection
Axon
Dendrite
Detected At The Immunological Synapse
I
E
At The Contact Zone Between Antigen-Presenting Dendritic Cells And T-Cells
Colocalizes With Cd6 And The Tcr/Cd3 Complex At The Immunological Synapse
Alternative Protein Names Cd166 Antigen protein
Activated Leukocyte Cell Adhesion Molecule protein
Ben protein
Protein Dm-Grasp protein
Cd Antigen Cd166 protein
Alcam protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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