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  • 产品名称：Mouse Angiopoietin-2/ANG-2/ANGPT2 protein (Recombinant) (C-6His) (STJP001922)

  • 产品型号：STJP001922
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Mouse Angiopoietin-2/ANG-2/ANGPT2 protein (Recombinant) (C-6His) (STJP001922)
详情介绍：
Host: HEK293 cells
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Mouse Angiopoietin-2/ANG-2/ANGPT2-C-6His protein was developed from hek293 cells and has a target region of C-6His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: Angpt2
Gene ID: 11601
Uniprot ID: ANGP2_MOUSE
Immunogen Region: Lys275-Phe496
Immunogen: Recombinant Mouse Angiopoietin-2/ANG-2/ANGPT2 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Lys275-Phe496) of mouse Angiopoietin-2/ANG-2/ANGPT2 (Accession #NP_031452.2) fused with a 6×His tag at
Function Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal. Involved in the regulation of lymphangiogenesis.
Protein Name Angiopoietin-2
Ang-2
Database Links Reactome: R-MMU-210993
Cellular Localisation Secreted
Alternative Protein Names Angiopoietin-2 protein
Ang-2 protein
Angpt2 protein
Agpt2 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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