产品详情
简单介绍:
Mouse B7-1/CD80 protein (Recombinant) (C-hFc & His) (STJP002738)
详情介绍:
Host: | HEK293 cells |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Mouse B7-1/CD80-C-hFc & His protein was developed from hek293 cells and has a target region of C-hFc & His. For use in research applications. |
Formulation: | Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Immunoreactivity: | Measured by its binding ability in a functional ELISA. Immobilized Recombinant Mouse CD80 at 500 ng/mL (100 Mu L/well) can bind Recombinant Human CTLA-4 with a linear range of 11-44 ng/mL. |
Gene Symbol: | Cd80 |
Gene ID: | 12519 |
Uniprot ID: | CD80_MOUSE |
Immunogen Region: | Val38-Lys245 |
Immunogen: | Recombinant Mouse B7-1/CD80 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Val38-Lys245) of mouse B7-1/CD80 (Accession #NP_033985.3) fused with a Fc, 6×His tag at the C-terminus. |
Function | Involved in the costimulatory signal essential for T lymphocytes activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor. |
Protein Name | T-Lymphocyte Activation Antigen Cd80 Activation B7-1 Antigen B7 Cd Antigen Cd80 |
Database Links | Reactome: R-MMU-1257604 Reactome: -MMU-389356 Reactome: -MMU-389357 Reactome: -MMU-389359 Reactome: -MMU-389513 Reactome: -MMU-6811558 |
Cellular Localisation | Membrane Single-Pass Type I Membrane Protein |
Alternative Protein Names | T-Lymphocyte Activation Antigen Cd80 protein Activation B7-1 Antigen protein B7 protein Cd Antigen Cd80 protein Cd80 protein B7 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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