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  • 产品名称：PREX2 Positive Control for STJ502653 peptide (STJ504800)

  • 产品型号：STJ504800-5
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
PREX2 Positive Control for STJ502653 peptide (STJ504800)
详情介绍：
Applications: WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: PREX2 Positive Control for STJ502653 is synthetically produced from the sequence and is suitable for use in western blot applications.
Formulation: Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Dilution Range: WB: 1:500-1:750
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: PREX2
Gene ID: 80243
Uniprot ID: PREX2_HUMAN
Specificity: This is positive control is recommended for use in combination with PREX2 antibody STJ502653.
Tissue Specificity Isoform 1 is highly expressed in skeletal muscle, heart and placenta, absent from peripheral blood leukocytes. Isoform 2 is expressed in skeletal muscle, kidney, small intestine, and placenta. Isoform 3 is expressed in the heart.
Function Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. Mediates the activation of RAC1 in a PI3K-dependent manner. May be an important mediator of Rac signaling, acting directly downstream of both G protein-coupled receptors and phosphoinositide 3-kinase.
Peptide Name Phosphatidylinositol 3 -4 -5-Trisphosphate-Dependent Rac Exchanger 2 Protein
P-Rex2
Ptdins(3 -4 -5-Dependent Rac Exchanger 2
Dep Domain-Containing Protein 2
Database Links Reactome: R-HSA-8948751
Reactome: R-HSA-8980692
Reactome: R-HSA-9013148
Reactome: R-HSA-9013149
Alternative Peptide Names Phosphatidylinositol 3 -4 -5-Trisphosphate-Dependent Rac Exchanger 2 Protein protein
P-Rex2 protein
Ptdins(3 -4 -5-Dependent Rac Exchanger 2 protein
Dep Domain-Containing Protein 2 protein
PREX2 protein
DEPDC2 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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