产品详情
简单介绍:
Mouse CD28 protein (Recombinant) (C-hFc&His) (STJP001225)
详情介绍:
Host: | HEK293 cells |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Mouse CD28-C-hFc&His protein was developed from hek293 cells and has a target region of C-hFc&His. For use in research applications. |
Formulation: | Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation. |
Immunoreactivity: | Measured by its binding ability in a functional ELISA. Immobilized Mouse CD86 Protein at 5 Mu g/mL (100 Mu L/well) can bind Mouse CD28 with a linear range of 0.0012-1.154 Mu g/mL. |
Gene Symbol: | Cd28 |
Gene ID: | 12487 |
Uniprot ID: | CD28_MOUSE |
Immunogen Region: | Asn20-Lys149 |
Immunogen: | Recombinant Mouse CD28 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Asn20-Lys149) of mouse CD28 (Accession #NP_031668.3) fused with a Fc, 6×His tag at the C-terminus. |
Function | Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation. |
Protein Name | T-Cell-Specific Surface Glycoprotein Cd28 Cd Antigen Cd28 |
Database Links | Reactome: R-MMU-1257604 Reactome: -MMU-389356 Reactome: -MMU-389357 Reactome: -MMU-389359 Reactome: -MMU-6811558 |
Cellular Localisation | Membrane Single-Pass Type I Membrane Protein |
Alternative Protein Names | T-Cell-Specific Surface Glycoprotein Cd28 protein Cd Antigen Cd28 protein Cd28 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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