产品详情
简单介绍:
Quiescin Q6 Positive Control peptide (STJ505083)
详情介绍:
Applications: | WB |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Quiescin Q6 Positive Control is synthetically produced from the sequence and is suitable for use in western blot applications. |
Formulation: | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
Dilution Range: | WB: 1:500 |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: | QSOX1 |
Gene ID: | 5768 |
Uniprot ID: | QSOX1_HUMAN |
Tissue Specificity | Expressed in heart, placenta, lung, liver, skeletal muscle, pancreas and very weakly in brain and kidney. |
Post Translational Modifications | N-glycosylated. O-glycosylated on Thr and Ser residues. |
Function | Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. Plays a role in disulfide bond formation in a variety of extracellular proteins. In fibroblasts, required for normal incorporation of laminin into the extracellular matrix, and thereby for normal cell-cell adhesion and cell migration. |
Peptide Name | Sulfhydryl Oxidase 1 Hqsox Quiescin Q6 |
Database Links | Reactome: R-HSA-114608 Reactome: R-HSA-381426 Reactome: R-HSA-6798695 Reactome: R-HSA-8957275 |
Cellular Localisation | Isoform 1: Golgi Apparatus Membrane Single-Pass Membrane Protein Secreted A Small Proportion Is Secreted Probably Via A Proteolytic Cleavage That Removes The Membrane Anchor Isoform 2: Secreted Found In The Extracellular Medium Of Quiescent Cells But Is Not Found In Proliferating Cells |
Alternative Peptide Names | Sulfhydryl Oxidase 1 protein Hqsox protein Quiescin Q6 protein QSOX1 protein QSCN6 protein UNQ2520 protein PRO6013 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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