产品详情
简单介绍:
Mouse CD40 (TNFRSF5) protein (Recombinant) (STJP000497)
详情介绍:
Host: | HEK293 |
Note: | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Mouse CD40 (TNFRSF5)-protein was developed from hek293. For use in research applications. |
Conjugation: | Unconjugated |
Formulation: | Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose. |
Storage Instruction: | Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA |
Endotoxin: | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
Immunoreactivity: | The activity was tested by the ability of immobilized recombinant mouse CD40 to bind Human CD40 Ligand with a linear range of 10-500 ng/ml NA |
Gene Symbol: | Cd40 |
Gene ID: | 21939 |
Uniprot ID: | TNR5_MOUSE |
Immunogen Region: | ECD |
Immunogen: | Optimized DNA sequence encoding extracellular domain of Mouse CD40 including a C-terminal His tag was expressed in HEK293 cells. NA |
Function | Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion. |
Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 5 B-Cell Surface Antigen Cd40 Bp50 Cd40l Receptor Cd Antigen Cd40 |
Database Links | Reactome: R-MMU-198933 Reactome: -MMU-5668541 Reactome: -MMU-5676594 |
Cellular Localisation | Isoform I: Cell Membrane Single-Pass Type I Membrane Protein Isoform Iii: Cell Membrane Isoform Iv: Cell Membrane Isoform V: Cell Membrane Isoform Ii: Secreted |
Alternative Protein Names | Tumor Necrosis Factor Receptor Superfamily Member 5 protein B-Cell Surface Antigen Cd40 protein Bp50 protein Cd40l Receptor protein Cd Antigen Cd40 protein Cd40 protein Tnfrsf5 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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