产品详情
查看大图

  • 产品名称：Mouse CD48 protein (Recombinant) (STJP000460)

  • 产品型号：STJP000460
  • 产品厂商：ST john's laboratory
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
Mouse CD48 protein (Recombinant) (STJP000460)
详情介绍：
Host: HEK293
Note: STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Mouse CD48-protein was developed from hek293. For use in research applications.
Conjugation: Unconjugated
Formulation: 0.2 Mu m filtered PBS solution, pH7.2.
Storage Instruction: Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA
Endotoxin: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA
Immunoreactivity: The activity was tested by immobilized recombinant mouse CD48 (10ug/ml) ability to bind recombinant CD2 with a linear range of 20-100 ng/ml. NA
Gene Symbol: Cd48
Gene ID: 12506
Uniprot ID: CD48_MOUSE
Immunogen Region: ECD
Immunogen: Optimized DNA sequence encoding extracellular domain of Mouse CD48including a C-terminal 6His tag was expressed in HEK293 cells. NA
Function Glycosylphosphatidylinositol (GPI)-anchored cell surface glycoprotein that interacts via its N-terminal immunoglobulin domain with cell surface receptors including 2B4/CD244 or CD2 to regulate immune cell function and activation. Participates in T-cell signaling transduction by associating with CD2 and efficiently bringing the Src family protein kinase LCK and LAT to the TCR/CD3 complex. In turn, promotes LCK phosphorylation and subsequent activation. Induces the phosphorylation of the cytoplasmic immunoreceptortyrosine switch motifs (ITSMs) of CD244 initiating a series of signaling events that leads to the generation of the immunological synapse and the directed release of cytolytic granules containing perforin and granzymes by T-lymphocytes and NK-cells.
Protein Name Cd48 Antigen
Bcm1 Surface Antigen
Blast-1
Hm48-1
Mrc Ox-45 Surface Antigen
Slam Family Member 2
Slamf2
Signaling Lymphocytic Activation Molecule 2
Sgp-60
Cd Antigen Cd48
Database Links Reactome: R-MMU-202733
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Secreted
Alternative Protein Names Cd48 Antigen protein
Bcm1 Surface Antigen protein
Blast-1 protein
Hm48-1 protein
Mrc Ox-45 Surface Antigen protein
Slam Family Member 2 protein
Slamf2 protein
Signaling Lymphocytic Activation Molecule 2 protein
Sgp-60 protein
Cd Antigen Cd48 protein
Cd48 protein
Bcm-1 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
姓名：
电话：
您的需求：
 

沪公网安备 31011002002624号