产品详情
简单介绍:
Mouse CD80 (B7-1) protein (Recombinant) (STJP000583)
详情介绍:
Host: | HEK293 |
Note: | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Mouse CD80 (B7-1)-protein was developed from hek293. For use in research applications. |
Conjugation: | Unconjugated |
Formulation: | Lyophilised from 0.2um filtered 50mM Tris, 100mM NaCl, pH 8.0. |
Storage Instruction: | Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA |
Endotoxin: | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
Gene Symbol: | Cd80 |
Gene ID: | 12519 |
Uniprot ID: | CD80_MOUSE |
Immunogen Region: | ECD |
Immunogen: | Optimized DNA sequence encoding extracellular domain of mouse CD80including a C-terminal 6His tag was expressed in HEK293 cells. NA |
Tissue Specificity | Expressed on activated B-cells, gamma interferon stimulated monocytes and non-circulating B-cell malignancies. |
Function | Involved in the costimulatory signal essential for T lymphocytes activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor. |
Protein Name | T-Lymphocyte Activation Antigen Cd80 Activation B7-1 Antigen B7 Cd Antigen Cd80 |
Database Links | Reactome: R-MMU-1257604 Reactome: -MMU-389356 Reactome: -MMU-389357 Reactome: -MMU-389359 Reactome: -MMU-389513 Reactome: -MMU-6811558 |
Cellular Localisation | Membrane Single-Pass Type I Membrane Protein |
Alternative Protein Names | T-Lymphocyte Activation Antigen Cd80 protein Activation B7-1 Antigen protein B7 protein Cd Antigen Cd80 protein Cd80 protein B7 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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