产品详情
查看大图

  • 产品名称：Anti-ARHGEF4 antibody (270-350 aa) (STJ191327)

  • 产品型号：STJ191327
  • 产品厂商：ST john's laboratory
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
Anti-ARHGEF4 antibody (270-350 aa) (STJ191327)
详情介绍：
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Rho guanine nucleotide exchange factor 4 (270-350 aa) is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
ELISA 1:5000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ARHGEF4
Gene ID: 50649
Uniprot ID: ARHG4_HUMAN
Immunogen Region: 270-350 aa
Specificity: ARHG4 Polyclonal Antibody detects endogenous levels of protein.
Immunogen: Synthesized peptide derived from the human protein at the amino acid range 270-350
Function Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Binding of APC may activate RAC1 GEF activity. The APC-ARHGEF4 complex seems to be involved in cell migration as well as in E-cadherin-mediated cell-cell adhesion. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.
Protein Name Rho Guanine Nucleotide Exchange Factor 4
Apc-Stimulated Guanine Nucleotide Exchange Factor 1
Asef
Asef1
Database Links Reactome: R-HSA-193648
Reactome: R-HSA-416482
Reactome: R-HSA-8980692
Reactome: R-HSA-9013148
Reactome: R-HSA-9013149
Cellular Localisation Isoform 3: Cytoplasm
Cell Projection
Ruffle Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Associated With Membrane Ruffles
Alternative Antibody Names Anti-Rho Guanine Nucleotide Exchange Factor 4 antibody
Anti-Apc-Stimulated Guanine Nucleotide Exchange Factor 1 antibody
Anti-Asef antibody
Anti-Asef1 antibody
Anti-ARHGEF4 antibody
Anti-KIAA1112 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
姓名：
电话：
您的需求：
 

沪公网安备 31011002002624号