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  • 产品名称：Mouse GAS-6 protein (Recombinant) (C-His) (STJP002438)

  • 产品型号：STJP002438-100
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Mouse GAS-6 protein (Recombinant) (C-His) (STJP002438)
详情介绍：
Host: HEK293 cells
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Mouse GAS-6-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Immunoreactivity: 1.Immobilized Mouse GAS6, His Tag at 5 Mu g/m l (100 Mu l/well) on the plate. Dose response curve for Human AXL, hFc Tag with the EC50 of 3.1ng/ml determined by ELISA (QC Test).2.Mouse AXL, His Tag immobilized on CM5 Chip can bind Mouse GAS6, His Tag
Gene Symbol: Gas6
Gene ID: 14456
Uniprot ID: GAS6_MOUSE
Immunogen Region: Val28-Pro674
Immunogen: Recombinant Mouse GAS-6 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Val28-Pro674) of mouse GAS-6 (Accession #NP_062394.2) fused with a 6×His tag at the C-terminus.
Function Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.
Protein Name Growth Arrest-Specific Protein 6
Gas-6
Axl Receptor Tyrosine Kinase Ligand
Database Links Reactome: R-MMU-114608
Reactome: -MMU-159763
Reactome: -MMU-159782
Reactome: -MMU-202733
Reactome: -MMU-381426
Reactome: -MMU-8957275
Cellular Localisation Secreted
Alternative Protein Names Growth Arrest-Specific Protein 6 protein
Gas-6 protein
Axl Receptor Tyrosine Kinase Ligand protein
Gas6 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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