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  • 产品名称：Mouse GDF15 protein (Recombinant) (N-hFc) {Biotin} (STJP001730)

  • 产品型号：STJP001730
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Mouse GDF15 protein (Recombinant) (N-hFc) {Biotin} (STJP001730)
详情介绍：
Host: HEK293
Note: STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Mouse GDF15-N-hFc protein was developed from hek293 and has a target region of N-hFc. For use in research applications.
Conjugation: Biotin
Formulation: Lyophilised from 0.2 µm filtered PBS solution pH7.4.
Dilution Range: Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20sec, 5K RPM
Storage Instruction: The lyophilized protein is stable for at least 1 year from date of receipt at-20°C.
Endotoxin: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg).
Gene Symbol: Gdf15
Gene ID: 23886
Uniprot ID: GDF15_MOUSE
Immunogen Region: Ser189-Ala303
Immunogen: DNA sequence encoding Moues GDF15 (Primary Amine Labeling) including a N-hFc tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology.
Function Regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. Binds to its receptor, GFRAL, and activates GFRAL-expressing neurons localized in the area postrema and nucleus tractus solitarius of the brainstem. It then triggers the activation of neurons localized within the parabrachial nucleus and central amygdala, which constitutes part of the 'emergency circuit' that shapes feeding responses to stressful conditions. On hepatocytes, inhibits growth hormone signaling.
Protein Name Growth/Differentiation Factor 15
Gdf-15
Macrophage Inhibitory Cytokine 1
Mic-1
Cellular Localisation Secreted
Alternative Protein Names Growth/Differentiation Factor 15 protein
Gdf-15 protein
Macrophage Inhibitory Cytokine 1 protein
Mic-1 protein
Gdf15 protein
Mic1 protein
Sbf protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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