产品详情
简单介绍:
Mouse GFRAL protein (Recombinant) (N-His & Avi) (STJP002081)
详情介绍:
Host: | HEK293 cells |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Mouse GFRAL-N-His & Avi protein was developed from hek293 cells and has a target region of N-His & Avi. For use in research applications. |
Formulation: | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 5 % trehalose is added as protectant before lyophilization. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | Gfral |
Gene ID: | 404194 |
Uniprot ID: | GFRAL_MOUSE |
Immunogen Region: | Gln20-Glu350 |
Immunogen: | Recombinant Mouse GFRAL Protein is produced by mammalian expression system. The target protein is expressed with sequence (Gln20-Glu350) of mouse GFRAL (Accession #) fused with a His and Avi Tag at the N-terminal.. |
Function | Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. Upon interaction with its ligand, GDF15, interacts with RET and induces cellular signaling through activation of MAPK- and AKT- signaling pathways. |
Protein Name | Gdnf Family Receptor Alpha-Like |
Cellular Localisation | Cell Membrane Single-Pass Membrane Protein Extracellular Side |
Alternative Protein Names | Gdnf Family Receptor Alpha-Like protein Gfral protein Gral protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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