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  • 产品名称：Human CLEC4K (C-Type Lectin Domain Family 4, Member K) Sandwich ELISA Kit Ready-To-Use (STJE0014365)

  • 产品型号：STJE0014365
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human CLEC4K (C-Type Lectin Domain Family 4, Member K) Sandwich ELISA Kit Ready-To-Use (STJE0014365)
详情介绍：
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.039ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This CLEC4K Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: CD207
Gene ID: 50489
Uniprot ID: CLC4K_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Tissue Specificity Exclusively expressed by Langerhans cells. Expressed in astrocytoma and malignant ependymoma, but not in normal brain tissues.
Post Translational Modifications
Function Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs).is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. Binds to high-mannose structures present on the envelope glycoprotein which is followed by subsequent targeting of the virus to the Birbeck granules leading to its rapid degradation.
Protein Name C-Type Lectin Domain Family 4 Member K
Langerin
Cd Antigen Cd207
Database Links Reactome: R-HSA-1236978
Cellular Localisation Membrane
Single-Pass Type Ii Membrane Protein
Found In Birbeck Granules (Bgs)
Which Are Organelles Consisting Of Superimposed And Zippered Membranes
Alternative ELISA Names C-Type Lectin Domain Family 4 Member K ELISA kit
Langerin ELISA kit
Cd Antigen Cd207 ELISA kit
CD207 ELISA kit
CLEC4K ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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