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  • 产品名称：Anti-ARSB antibody (404-533) (STJ116444)

  • 产品型号：STJ116444
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-ARSB antibody (404-533) (STJ116444)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ARSB (404-533) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ARSB
Gene ID: 411
Uniprot ID: ARSB_HUMAN
Immunogen Region: 404-533
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 404-533 of human ARSB (NP_000037.2).
Immunogen Sequence: PCPRNSMAPAKDDSSLPEYS AFNTSVHAAIRHGNWKLLTG YPGCGYWFPPPSQYNVSEIP SSDPPTKTLWLFDIDRDPEE RHDLSREYPHIVTKLLSRLQ FYHKHSVPVYFPAQDPRCDP KATGVWGPWM
Post Translational Modifications The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. This post-translational modification is severely defective in multiple sulfatase deficiency (MSD).
Function Removes sulfate groups from chondroitin-4-sulfate (C4S) and regulates its degradation. Involved in the regulation of cell adhesion, cell migration and invasion in colonic epithelium. In the central nervous system, is a regulator of neurite outgrowth and neuronal plasticity, acting through the control of sulfate glycosaminoglycans and neurocan levels.
Protein Name Arylsulfatase B
Asb
N-Acetylgalactosamine-4-Sulfatase
G4s
Database Links Reactome: R-HSA-1660662
Reactome: R-HSA-1663150
Reactome: R-HSA-2024101
Reactome: R-HSA-2206285
Reactome: R-HSA-6798695
Cellular Localisation Lysosome
Cell Surface
Alternative Antibody Names Anti-Arylsulfatase B antibody
Anti-Asb antibody
Anti-N-Acetylgalactosamine-4-Sulfatase antibody
Anti-G4s antibody
Anti-ARSB antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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