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  • 产品名称：Anti-ASB4 antibody (1-300) (STJ119327)

  • 产品型号：STJ119327
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-ASB4 antibody (1-300) (STJ119327)
详情介绍：
Host: Rabbit
Applications: IHC
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ASB4 (1-300) is suitable for use in Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: IHC-P 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ASB4
Gene ID: 51666
Uniprot ID: ASB4_HUMAN
Immunogen Region: 1-300
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human ASB4 (NP_665879.1).
Immunogen Sequence: MDGTTAPVTKSGAAKLVKRN FLEALKSNDFGKLKAILIQR QIDVDTVFEVEDENMVLASY KQGYWLPSYKLKSSWATGLH LSVLFGHVECLLVLLDHNAT INCRPNGKTPLHVACEMANV DCVKILCDRGAKLNCYSLSG HTALHFCTTPSSILCAKQLV WRGANVNMKTNNQDEETPLH TAAHFGLSELVAFYVEHGAI VDSVNAHMETPLAIAAYWAL RFKEQEYSTEHHLVCRMLL
Post Translational Modifications Hydroxylation at Asn-246 by HIF1AN may provide an oxygen-dependent regulation mechanism for the function of ASB4 in promoting vascular differentiation.
Function Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes differentiation and maturation of the vascular lineage by an oxygen-dependent mechanism.
Protein Name Ankyrin Repeat And Socs Box Protein 4
Asb-4
Database Links Reactome: R-HSA-8951664
Reactome: R-HSA-983168
Alternative Antibody Names Anti-Ankyrin Repeat And Socs Box Protein 4 antibody
Anti-Asb-4 antibody
Anti-ASB4 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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