产品详情
简单介绍:
SLC26A3 Blocking Peptide for STJ506235 peptide (STJ505913)
详情介绍:
Applications: | Immunodepletion/Immunocompetition |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | SLC26A3 Blocking Peptide for STJ506235 is synthetically produced from the 650-700 sequence and is suitable for use in western blot applications. |
Formulation: | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: | SLC26A3 |
Gene ID: | 1811 |
Uniprot ID: | S26A3_HUMAN |
Immunogen Region: | 650-700 |
Specificity: | This blocking peptide is recommended for use in combination with SLC26A3 antibody, STJ506235 |
Immunogen: | Synthetic peptide corresponding to amino acids within region 650-700 on human SCL26A3 protein. |
Tissue Specificity | Expressed in the colon. Expression is significantly decreased in adenomas (polyps) and adenocarcinomas of the colon. |
Post Translational Modifications | N-glycosylation is required for efficient cell surface expression, and protection from proteolytic degradation. |
Function | Mediates chloride-bicarbonate exchange with a chloride bicarbonate stoichiometry of 2:1 in the intestinal epithelia. Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation. |
Peptide Name | Chloride Anion Exchanger Down-Regulated In Adenoma Protein Dra Solute Carrier Family 26 Member 3 |
Database Links | Reactome: R-HSA-427601 Reactome: R-HSA-5619085 |
Cellular Localisation | Apical Cell Membrane Multi-Pass Membrane Protein Membrane Cell Membrane Localized In Sperm Membranes Midpiece Of Sperm Tail Colocalizes With Cftr At The Midpiece Of Sperm Tail |
Alternative Peptide Names | Chloride Anion Exchanger protein Down-Regulated In Adenoma protein Protein Dra protein Solute Carrier Family 26 Member 3 protein SLC26A3 protein DRA protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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