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  • 产品名称：Anti-ASIC2 antibody (120-400) (STJ112520)

  • 产品型号：STJ112520
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-ASIC2 antibody (120-400) (STJ112520)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ASIC2 (120-400) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:1000-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ASIC2
Gene ID: 40
Uniprot ID: ASIC2_HUMAN
Immunogen Region: 120-400
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 120-400 of human ASIC2 (NP_001085.2).
Immunogen Sequence: NLQIPDPHLADPSVLEALRQ KANFKHYKPKQFSMLEFLHR VGHDLKDMMLYCKFKGQECG HQDFTTVFTKYGKCYMFNSG EDGKPLLTTVKGGTGNGLEI MLDIQQDEYLPIWGETEETT FEAGVKVQIHSQSEPPFIQE LGFGVAPGFQTFVATQEQRL TYLPPPWGECRSSEMGLDFF PVYSITACRIDCETRYIVEN CNCRMVHMPGDAPFCTPEQH KECAEPALGLLAEKDSNYC
Tissue Specificity Brain and spinal cord. Isoform 1 is also detected in testis, liver, colon and ovary.
Function Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Li(+) and K(+). Generates a biphasic current with a fast inactivating and a slow sustained phase. Heteromeric channel assembly seems to modulate.
Protein Name Acid-Sensing Ion Channel 2
Asic2
Amiloride-Sensitive Brain Sodium Channel
Amiloride-Sensitive Cation Channel 1 - Neuronal
Amiloride-Sensitive Cation Channel Neuronal 1
Brain Sodium Channel 1
Bnc1
Bnac1
Mammalian Degenerin Homolog
Mdeg
Database Links Reactome: R-HSA-2672351
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Localized At The Plasma Membrane Of Neurons
In The Soma And Punctated Peripheral Processes
Alternative Antibody Names Anti-Acid-Sensing Ion Channel 2 antibody
Anti-Asic2 antibody
Anti-Amiloride-Sensitive Brain Sodium Channel antibody
Anti-Amiloride-Sensitive Cation Channel 1 - Neuronal antibody
Anti-Amiloride-Sensitive Cation Channel Neuronal 1 antibody
Anti-Brain Sodium Channel 1 antibody
Anti-Bnc1 antibody
Anti-Bnac1 antibody
Anti-Mammalian Degenerin Homolog antibody
Anti-Mdeg antibody
Anti-ASIC2 antibody
Anti-ACCN antibody
Anti-ACCN1 antibody
Anti-BNAC1 antibody
Anti-MDEG antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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