产品详情
简单介绍:
Human CPLX2 (Complexin 2) Competitive ELISA Kit Ready-To-Use (STJE0014481)
详情介绍:
Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.084ng/mL |
Detection Limit: | 0.312-20ng/mL |
Short Description: | This CPLX2 Competitive ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 2.5 hrs |
Gene Symbol: | CPLX2 |
Gene ID: | 10814 |
Uniprot ID: | CPLX2_HUMAN |
Immunogen Region: | Ready-To-Use |
Sample Type: | serum, plasma or other biological fluids. |
Tissue Specificity | Nervous system. In hippocampus and cerebellum, expressed mainly by excitatory neurons. Down-regulated in brain cortex from patients suffering from Huntington disease, bipolar disorder or major depression. Down-regulated in cerebellum from patients with schizophrenia. |
Post Translational Modifications | |
Function | Negatively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Positively regulates a late step in exocytosis of various cytoplasmic vesicles, such as synaptic vesicles and other secretory vesicles. Also involved in mast cell exocytosis. |
Protein Name | Complexin-2 Complexin Ii Cpx Ii Synaphin-1 |
Database Links | |
Cellular Localisation | Cytoplasm Cytosol Presynapse Nucleus Perikaryon Translocated From The Perikaryon To The Presynaptic Terminals During Maturation Of Neuronal Cells In Mast Cells Cytosol And Nucleus Becomes Enriched Near Plasma Membrane Following Stimulation |
Alternative ELISA Names | Complexin-2 ELISA kit Complexin Ii ELISA kit Cpx Ii ELISA kit Synaphin-1 ELISA kit CPLX2 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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