产品详情
简单介绍:
Mouse SELP/P-Selectin/CD62P protein (Recombinant) (C-His) (STJP001133)
详情介绍:
Host: | HEK293 cells |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Mouse SELP/P-Selectin/CD62P-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
Formulation: | Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation. |
Immunoreactivity: | Measured by the ability of the immobilized protein to support the adhesion of U937 cells. When 5 x 10E4 cells/well are added to SELP-coated plates (10 Mu g/mL and 100 Mu L/well) , approximately >40% cells will adhere specifically after 1 hour at 37 ° |
Gene Symbol: | Selp |
Gene ID: | 20344 |
Uniprot ID: | LYAM3_MOUSE |
Immunogen: | Recombinant Mouse SELP/P-Selectin/CD62P Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Trp42-Ala709) of mouse P-Selectin/CD62P (Accession #NP_035477.1.) fused with a 6×His tag at the C-terminus. |
Function | Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with SELPLG. |
Protein Name | P-Selectin Cd62 Antigen-Like Family Member P Granule Membrane Protein 140 Gmp-140 Leukocyte-Endothelial Cell Adhesion Molecule 3 Lecam3 Platelet Activation Dependent Granule-External Membrane Protein Padgem Cd Antigen Cd62p |
Database Links | Reactome: R-MMU-114608 Reactome: -MMU-202733 |
Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein |
Alternative Protein Names | P-Selectin protein Cd62 Antigen-Like Family Member P protein Granule Membrane Protein 140 protein Gmp-140 protein Leukocyte-Endothelial Cell Adhesion Molecule 3 protein Lecam3 protein Platelet Activation Dependent Granule-External Membrane Protein protein Padgem protein Cd Antigen Cd62p protein Selp protein Grmp protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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