产品详情
简单介绍:
Mouse Siglec-3/CD33 protein (Recombinant) (C-His) (STJP001494)
详情介绍:
Host: | HEK293 cells |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Mouse Siglec-3/CD33-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
Formulation: | Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
Gene Symbol: | Cd33 |
Gene ID: | 12489 |
Uniprot ID: | CD33_MOUSE |
Immunogen: | Recombinant Mouse Siglec-3/CD33 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Asp18-Glu240) of mouse Siglec3/CD33 (Accession #NP_001104528.1) fused with a 6×His tag at the C-terminus. |
Post Translational Modifications | Glycosylated. Phosphorylation is involved in binding to PTPN6 and PTPN11. |
Function | Sialic-acid-binding immunoglobulin-like lectin (Siglec) that plays a role in mediating cell-cell interactions and in maintaining immune cells in a resting state. Preferentially binds sialic acid to the short O-linked glycans of certain mucins. |
Protein Name | Myeloid Cell Surface Antigen Cd33 Sialic Acid-Binding Ig-Like Lectin 3 Siglec-3 Cd Antigen Cd33 |
Database Links | Reactome: R-MMU-198933 Reactome: -MMU-6798695 |
Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein |
Alternative Protein Names | Myeloid Cell Surface Antigen Cd33 protein Sialic Acid-Binding Ig-Like Lectin 3 protein Siglec-3 protein Cd Antigen Cd33 protein Cd33 protein Siglec3 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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