产品详情
简单介绍:
Anti-ATAD1 antibody (STJA0004607)
详情介绍:
Host: | Rabbit |
Applications: | IHC/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Outer Mitochondrial Transmembrane Helix Translocase is suitable for use in Immunohistochemistry and ELISA research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
Purification: | Antigen affinity purification |
Concentration: | 0.9 mg/mL |
Dilution Range: | IHC 1:40-1:200 |
Storage Instruction: | Store at-20°C for long term, and avoid freeze-thaw cycles. |
Gene Symbol: | ATAD1 |
Gene ID: | 84896 |
Uniprot ID: | ATAD1_HUMAN |
Immunogen: | Fusion protein of human ATAD1 |
Function | Outer mitochondrial translocase required to remove mislocalized tail-anchored transmembrane proteins on mitochondria. Specifically recognizes and binds tail-anchored transmembrane proteins: acts as a dislocase that mediates the ATP-dependent extraction of mistargeted tail-anchored transmembrane proteins from the mitochondrion outer membrane. Also plays a critical role in regulating the surface expression of AMPA receptors (AMPAR), thereby regulating synaptic plasticity and learning and memory. Required for NMDA-stimulated AMPAR internalization and inhibition of GRIA1 and GRIA2 recycling back to the plasma membrane.these activities are ATPase-dependent. |
Protein Name | Outer Mitochondrial Transmembrane Helix Translocase Atpase Family Aaa Domain-Containing Protein 1 Hatad1 Thorase |
Database Links | Reactome: R-HSA-9603798 |
Cellular Localisation | Mitochondrion Outer Membrane Single-Pass Membrane Protein Peroxisome Membrane Postsynaptic Cell Membrane |
Alternative Antibody Names | Anti-Outer Mitochondrial Transmembrane Helix Translocase antibody Anti-Atpase Family Aaa Domain-Containing Protein 1 antibody Anti-Hatad1 antibody Anti-Thorase antibody Anti-ATAD1 antibody Anti-FNP001 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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