产品详情
简单介绍:
Syndecan-1 Blocking Peptide peptide (STJ504976)
详情介绍:
Applications: | Immunodepletion/Immunocompetition |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Syndecan-1 Blocking Peptide is synthetically produced from the 1-100 sequence and is suitable for use in western blot applications. |
Formulation: | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: | SDC1 |
Gene ID: | 6382 |
Uniprot ID: | SDC1_HUMAN |
Immunogen Region: | 1-100 |
Immunogen: | N-epitope synthetic peptide taken within amino acid region 1-100 on human Syndecan-1 protein. |
Tissue Specificity | Detected in placenta (at protein level). Detected in fibroblasts (at protein level). |
Post Translational Modifications | Shedding is enhanced by a number of factors such as heparanase, thrombin or EGF. Also by stress and wound healing. PMA-mediated shedding is inhibited by TIMP3. |
Function | Cell surface proteoglycan that contains both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP. Able to induce its own expression in dental mesenchymal cells and also in the neighboring dental epithelial cells via an MSX1-mediated pathway. |
Peptide Name | Syndecan-1 Synd1 Cd Antigen Cd138 |
Database Links | Reactome: R-HSA-1971475 Reactome: R-HSA-2022928 Reactome: R-HSA-2024096 Reactome: R-HSA-202733 Reactome: R-HSA-3000170 Reactome: R-HSA-3560783 Reactome: R-HSA-3560801 Reactome: R-HSA-3656237 Reactome: R-HSA-3656253 Reactome: R-HSA-4420332 Reactome: R-HSA-449836 Reactome: R-HSA-9694614 Reactome: R-HSA-975634 |
Cellular Localisation | Membrane Single-Pass Type I Membrane Protein Secreted Extracellular Exosome Shedding Of The Ectodomain Produces A Soluble Form |
Alternative Peptide Names | Syndecan-1 protein Synd1 protein Cd Antigen Cd138 protein SDC1 protein SDC protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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