产品详情
简单介绍:
Rat CD38 protein (Recombinant) (STJP000634)
详情介绍:
Host: | HEK293 |
Note: | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Rat CD38-protein was developed from hek293. For use in research applications. |
Conjugation: | Unconjugated |
Formulation: | 0.2 Mu m filtered PBS solution, pH7.2. |
Storage Instruction: | Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA |
Endotoxin: | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
Gene Symbol: | Cd38 |
Gene ID: | 25668 |
Uniprot ID: | CD38_RAT |
Immunogen Region: | ECD |
Immunogen: | Optimized DNA sequence encoding extracellular domain of Rat CD38 including a C-terminal 6His tag was expressed in HEK293 cells. NA |
Tissue Specificity | Spleen, liver, heart, thymus, thyroid gland, ileum, colon, cerebellum, salivary gland, adrenal gland, jejunum, islets of Langerhans and osteoclasts. |
Function | Synthesizes the second messengers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion, the latter a Ca(2+) mobilizer. Also has cADPR hydrolase activity. Regulates osteoclastic bone resorption, probably via production of cyclic ADP-ribose and triggering of a cytosolic calcium ion signal through ryanodine receptor activation. |
Protein Name | Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 1 2'-Phospho-Adp-Ribosyl Cyclase 2'-Phospho-Adp-Ribosyl Cyclase/2'-Phospho-Cyclic-Adp-Ribose Transferase 2'-Phospho-Cyclic-Adp-Ribose Transferase Adp-Ribosyl Cyclase 1 Adprc 1 Cd38h Cyclic Adp-Ribose Hydrolase 1 Cadpr Hydrolase 1 Cd Antigen Cd38 |
Database Links | Reactome: R-RNO-196807 |
Cellular Localisation | Cell Membrane Single-Pass Type Ii Membrane Protein |
Alternative Protein Names | Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 1 protein 2'-Phospho-Adp-Ribosyl Cyclase protein 2'-Phospho-Adp-Ribosyl Cyclase/2'-Phospho-Cyclic-Adp-Ribose Transferase protein 2'-Phospho-Cyclic-Adp-Ribose Transferase protein Adp-Ribosyl Cyclase 1 protein Adprc 1 protein Cd38h protein Cyclic Adp-Ribose Hydrolase 1 protein Cadpr Hydrolase 1 protein Cd Antigen Cd38 protein Cd38 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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