产品详情
简单介绍:
Anti-ATP2A3 antibody (360-600) (STJ116445)
详情介绍:
Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-ATP2A3 (360-600) is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | ATP2A3 |
Gene ID: | 489 |
Uniprot ID: | AT2A3_HUMAN |
Immunogen Region: | 360-600 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 360-600 of human ATP2A3 (NP_005164.2). |
Immunogen Sequence: | QMSVCRMFVVAEADAGSCLL HEFTISGTTYTPEGEVRQGD QPVRCGQFDGLVELATICAL CNDSALDYNEAKGVYEKVGE ATETALTCLVEKMNVFDTDL QALSRVERAGACNTVIKQLM RKEFTLEFSRDRKSMSVYCT PTRPHPTGQGSKMFVKGAPE SVIERCSSVRVGSRTAPLTP TSREQILAKIRDWGSGSDTL RCLALATRDAPPRKEDMELD DCSKFVQYETDLTFVGCVG |
Tissue Specificity | Found in most tissues. Most abundant in thymus, trachea, salivary gland, spleen, bone marrow, lymph node, peripheral leukocytes, pancreas and colon. Also detected in fetal tissues. Expressed in cell lineages of hematopoietic, epithelial, or embryonic origin and also expressed in several cancer cell lines. |
Function | This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Transports calcium ions from the cytosol into the sarcoplasmic/endoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction. |
Protein Name | Sarcoplasmic/Endoplasmic Reticulum Calcium Atpase 3 Serca3 Sr Ca(2+-Atpase 3 Calcium Pump 3 |
Database Links | Reactome: R-HSA-1912420 Reactome: R-HSA-418359 Reactome: R-HSA-5578775 Reactome: R-HSA-936837 |
Cellular Localisation | Nucleus Membrane Multi-Pass Membrane Protein Endoplasmic Reticulum Membrane Sarcoplasmic Reticulum Membrane |
Alternative Antibody Names | Anti-Sarcoplasmic/Endoplasmic Reticulum Calcium Atpase 3 antibody Anti-Serca3 antibody Anti-Sr Ca(2+-Atpase 3 antibody Anti-Calcium Pump 3 antibody Anti-ATP2A3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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