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  • 产品名称：Anti-ATP5C1 antibody (26-298) (STJ117452)

  • 产品型号：STJ117452
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-ATP5C1 antibody (26-298) (STJ117452)
详情介绍：
Host: Rabbit
Applications: WB/IHC/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ATP5C1 (26-298) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:200-1:2000
IHC-P 1:50-1:200
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ATP5F1C
Gene ID: 509
Uniprot ID: ATPG_HUMAN
Immunogen Region: 26-298
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 26-298 of human ATP5C1 (NP_001001973.1).
Immunogen Sequence: ATLKDITRRLKSIKNIQKIT KSMKMVAAAKYARAERELKP ARIYGLGSLALYEKADIKGP EDKKKHLLIGVSSDRGLCGA IHSSIAKQMKSEVATLTAAG KEVMLVGIGDKIRGILYRTH SDQFLVAFKEVGRKPPTFGD ASVIALELLNSGYEFDEGSI IFNKFRSVISYKTEEKPIFS LNTVASADSMSIYDDIDADV LQNYQEYNLANIIYYSLKES TTSEQSARMTAMDNASKNA
Tissue Specificity Isoform Heart is expressed specifically in the heart and skeletal muscle, which require rapid energy supply. Isoform Liver is expressed in the brain, liver and kidney. Isoform Heart and Isoform Liver are expressed in the skin, intestine, stomach and aorta.
Function Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and the central stalk which is part of the complex rotary element. The gamma subunit protrudes into the catalytic domain formed of alpha(3)beta(3). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.
Protein Name Atp Synthase Subunit Gamma - Mitochondrial
Atp Synthase F1 Subunit Gamma
F-Atpase Gamma Subunit
Database Links Reactome: R-HSA-163210
Reactome: R-HSA-8949613
Cellular Localisation Mitochondrion Inner Membrane
Peripheral Membrane Protein
Matrix Side
Alternative Antibody Names Anti-Atp Synthase Subunit Gamma - Mitochondrial antibody
Anti-Atp Synthase F1 Subunit Gamma antibody
Anti-F-Atpase Gamma Subunit antibody
Anti-ATP5F1C antibody
Anti-ATP5C antibody
Anti-ATP5C1 antibody
Anti-ATP5CL1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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