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  • 产品名称：Human CYP2C19 (Cytochrome P450 2C19) Sandwich ELISA Kit (STJE0008318)

  • 产品型号：STJE0008318
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human CYP2C19 (Cytochrome P450 2C19) Sandwich ELISA Kit (STJE0008318)
详情介绍：
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.056ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This CYP2C19 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: CYP2C19
Gene ID: 1557
Uniprot ID: CP2CJ_HUMAN
Sample Type: serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Tissue Specificity
Post Translational Modifications
Function A cytochrome P450 monooxygenase involved in the metabolism of polyunsaturated fatty acids (PUFA). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates PUFA specifically at the omega-1 position. Catalyzes the epoxidation of double bonds of PUFA. Also metabolizes plant monoterpenes such as limonene. Oxygenates (R)- and (S)-limonene to produce carveol and perillyl alcohol. Responsible for the metabolism of a number of therapeutic agents such as the anticonvulsant drug S-mephenytoin, omeprazole, proguanil, certain barbiturates, diazepam, propranolol, citalopram and imipramine. Hydroxylates fenbendazole at the 4' position.
Protein Name Cytochrome P450 2c19
(R-Limonene 6-Monooxygenase
(S-Limonene 6-Monooxygenase
(S-Limonene 7-Monooxygenase
Cypiic17
Cypiic19
Cytochrome P450-11a
Cytochrome P450-254c
Fenbendazole Monooxygenase
4'-Hydroxylating
Mephenytoin 4-Hydroxylase
Database Links Reactome: R-HSA-211981
Reactome: R-HSA-211999
Reactome: R-HSA-2142670
Reactome: R-HSA-2142816
Reactome: R-HSA-9749641
Cellular Localisation Endoplasmic Reticulum Membrane
Peripheral Membrane Protein
Microsome Membrane
Alternative ELISA Names Cytochrome P450 2c19 ELISA kit
(R-Limonene 6-Monooxygenase ELISA kit
(S-Limonene 6-Monooxygenase ELISA kit
(S-Limonene 7-Monooxygenase ELISA kit
Cypiic17 ELISA kit
Cypiic19 ELISA kit
Cytochrome P450-11a ELISA kit
Cytochrome P450-254c ELISA kit
Fenbendazole Monooxygenase ELISA kit
4'-Hydroxylating ELISA kit
Mephenytoin 4-Hydroxylase ELISA kit
CYP2C19 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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