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  • 产品名称：Anti-AP3B2 antibody (833-1082) (STJ115752)

  • 产品型号：STJ115752
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-AP3B2 antibody (833-1082) (STJ115752)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-AP3B2 (833-1082) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: AP3B2
Gene ID: 8120
Uniprot ID: AP3B2_HUMAN
Immunogen Region: 833-1082
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 833-1082 of human AP3B2 (NP_004635.2).
Immunogen Sequence: AADLEGLTLTDSTLVPSLLS PVSGVGRQELLHRVAGEGLA VDYTFSRQPFSGDPHMVSVH IHFSNSSDTPIKGLHVGTPK LPAGISIQEFPEIESLAPGE SATAVMGINFCDSTQAANFQ LCTQTRQFYVSIQPPVGELM APVFMSENEFKKEQGKLMGM NEITEKLMLPDTCRSDHIVV QKVTATANLGRVPCGTSDEY RFAGRTLTGGSLVLLTLDAR PAGAAQLTVNSEKMVIGTM
Tissue Specificity Isoform 1 expression is specific to nervous system. Expressed in nerve terminal and cell body, and is associated with nerve-terminal vesicles. Expression seen in Purkinje cells, cortical neurons, neuroectodermal tumors and graded in cerebral cortex (deeper layers exhibit stronger expression). Isoform 2 is expressed at high levels in brain and testis.
Function Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
Protein Name Ap-3 Complex Subunit Beta-2
Adaptor Protein Complex Ap-3 Subunit Beta-2
Adaptor-Related Protein Complex 3 Subunit Beta-2
Beta-3b-Adaptin
Clathrin Assembly Protein Complex 3 Beta-2 Large Chain
Neuron-Specific Vesicle Coat Protein Beta-Nap
Cellular Localisation Cytoplasmic Vesicle
Clathrin-Coated Vesicle Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Golgi Apparatus
Component Of The Coat Surrounding The Cytoplasmic Face Of Coated Vesicles Located At The Golgi Complex
Alternative Antibody Names Anti-Ap-3 Complex Subunit Beta-2 antibody
Anti-Adaptor Protein Complex Ap-3 Subunit Beta-2 antibody
Anti-Adaptor-Related Protein Complex 3 Subunit Beta-2 antibody
Anti-Beta-3b-Adaptin antibody
Anti-Clathrin Assembly Protein Complex 3 Beta-2 Large Chain antibody
Anti-Neuron-Specific Vesicle Coat Protein Beta-Nap antibody
Anti-AP3B2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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