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  • 产品名称：Anti-BAAT antibody (309-418) (STJ29960)

  • 产品型号：STJ29960
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-BAAT antibody (309-418) (STJ29960)
详情介绍：
Host: Rabbit
Applications: WB/IHC/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-BAAT (309-418) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IHC-P 1:100-1:500
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: BAAT
Gene ID: 570
Uniprot ID: BAAT_HUMAN
Immunogen Region: 309-418
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 309-418 of human BAAT (NP_001692.1).
Immunogen Sequence: YLFPIEEAQGQFLFIVGEGD KTINSKAHAEQAIGQLKRHG KNNWTLLSYPGAGHLIEPPY SPLCCASTTHDLRLHWGGEV IPHAAAQEHAWKEIQRFLRK HLIPDVTSQL
Tissue Specificity Expressed in the gallbladder mucosa and pancreas. Expressed in hepatocytes (at protein level).
Function Catalyzes the amidation of bile acids (BAs) with the amino acids taurine and glycine. More than 95% of the BAs are N-acyl amidates with glycine and taurine. Amidation of BAs in the liver with glycine or taurine prior to their excretion into bile is an important biochemical event in bile acid metabolism. This conjugation (or amidation) plays several important biological roles in that it promotes the secretion of BAs and cholesterol into bile and increases the detergent properties of BAs in the intestine, which facilitates lipid and vitamin absorption. May also act as an acyl-CoA thioesterase that regulates intracellular levels of free fatty acids. In vitro, catalyzes the hydrolysis of long- and very long-chain saturated acyl-CoAs to the free fatty acid and coenzyme A (CoASH), and conjugates glycine to these acyl-CoAs.
Protein Name Bile Acid-Coa -Amino Acid N-Acyltransferase
Bacat
Bat
Bile Acid-Coa Thioesterase
Choloyl-Coa Hydrolase
Glycine N-Choloyltransferase
Long-Chain Fatty-Acyl-Coa Hydrolase
Database Links Reactome: R-HSA-159418
Reactome: R-HSA-193368
Reactome: R-HSA-9033241
Cellular Localisation Cytoplasm
Cytosol
Peroxisome
Alternative Antibody Names Anti-Bile Acid-Coa -Amino Acid N-Acyltransferase antibody
Anti-Bacat antibody
Anti-Bat antibody
Anti-Bile Acid-Coa Thioesterase antibody
Anti-Choloyl-Coa Hydrolase antibody
Anti-Glycine N-Choloyltransferase antibody
Anti-Long-Chain Fatty-Acyl-Coa Hydrolase antibody
Anti-BAAT antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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