产品详情
简单介绍:
Human DSTYK (Dual Serine/Threonine And Tyrosine Protein Kinase) Sandwich ELISA Kit (STJE0008524)
详情介绍:
Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.055ng/mL |
Detection Limit: | 0.156-10ng/mL |
Short Description: | This DSTYK Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Gene Symbol: | DSTYK |
Gene ID: | 25778 |
Uniprot ID: | DUSTY_HUMAN |
Sample Type: | tissue homogenates or other biological fluids. |
Tissue Specificity | Predominantly expressed in skeletal muscle and testis. Expressed in basolateral and apical membranes of all tubular epithelia. Expressed in thin ascending limb of the loop of Henle and the distal convoluted tubule. Expressed in all layers of transitional ureteric epithelium and in the ureteric smooth-muscle cells. Weakly expressed in heart, brain, placenta, kidney, pancreas, spleen, thymus, prostate, uterus, small intestine, white blood cells, stomach, spinal cord and adrenal gland. Is widely distributed in the CNS. Also detected in several tumor cell lines. Expressed in the skin. |
Post Translational Modifications | |
Function | Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. Involved in the regulation of both caspase-dependent apoptosis and caspase-independent cell death. In the skin, it plays a predominant role in suppressing caspase-dependent apoptosis in response to UV stress in a range of dermal cell types. |
Protein Name | Dual Serine/Threonine And Tyrosine Protein Kinase Dusty Protein Kinase Dusty Pk Rip-Homologous Kinase Receptor-Interacting Serine/Threonine-Protein Kinase 5 Sugen Kinase 496 Sgk496 |
Database Links | |
Cellular Localisation | Cytoplasm Cell Membrane Apical Cell Membrane Basolateral Cell Membrane Cell Junction Detected At Apical Cell-Cell Junctions Colocalized With Fgf Receptors To The Cell Membrane Detected In Basolateral And Apical Membranes Of All Tubular Epithelia |
Alternative ELISA Names | Dual Serine/Threonine And Tyrosine Protein Kinase ELISA kit Dusty Protein Kinase ELISA kit Dusty Pk ELISA kit Rip-Homologous Kinase ELISA kit Receptor-Interacting Serine/Threonine-Protein Kinase 5 ELISA kit Sugen Kinase 496 ELISA kit Sgk496 ELISA kit DSTYK ELISA kit KIAA0472 ELISA kit RIP5 ELISA kit RIPK5 ELISA kit SGK496 ELISA kit HDCMD38P ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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