产品详情
简单介绍:
Human E2F2 (E2F Transcription Factor 2) Sandwich ELISA Kit (STJE0008547)
详情介绍:
Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.068ng/mL |
Detection Limit: | 0.156-10ng/mL |
Short Description: | This E2F2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Gene Symbol: | E2F2 |
Gene ID: | 1870 |
Uniprot ID: | E2F2_HUMAN |
Sample Type: | tissue homogenates, cell lysates or other biological fluids. |
Tissue Specificity | Highest level of expression is found in placenta, low levels are found in lung. Found as well in many immortalized cell lines derived from tumor samples. |
Post Translational Modifications | Phosphorylated by CDK2 and cyclin A-CDK2 in the S-phase. |
Function | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTCCGCGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from g1 to s phase. E2F2 binds specifically to RB1 in a cell-cycle dependent manner. |
Protein Name | Transcription Factor E2f2 E2f-2 |
Database Links | Reactome: R-HSA-2559580 Reactome: R-HSA-2559585 Reactome: R-HSA-69231 Reactome: R-HSA-9661069 |
Cellular Localisation | Nucleus |
Alternative ELISA Names | Transcription Factor E2f2 ELISA kit E2f-2 ELISA kit E2F2 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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