产品详情
简单介绍:
Human EAAT4 (Excitatory Amino Acid Transporter 4) Sandwich ELISA Kit (STJE0008555)
详情介绍:
Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.129ng/mL |
Detection Limit: | 0.312-20ng/mL |
Short Description: | This EAAT4 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Gene Symbol: | SLC1A6 |
Gene ID: | 6511 |
Uniprot ID: | EAA4_HUMAN |
Sample Type: | tissue homogenates or other biological fluids. |
Tissue Specificity | Brain, mainly in the cerebellum. Expressed densely and selectively in cell bodies of Purkinje cells. |
Post Translational Modifications | |
Function | Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport.this avoids the accumulation of negative charges due to aspartate and Na(+) symport. Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate (Probable). |
Protein Name | Excitatory Amino Acid Transporter 4 Sodium-Dependent Glutamate/Aspartate Transporter Solute Carrier Family 1 Member 6 |
Database Links | Reactome: R-HSA-210500 Reactome: R-HSA-425393 |
Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein |
Alternative ELISA Names | Excitatory Amino Acid Transporter 4 ELISA kit Sodium-Dependent Glutamate/Aspartate Transporter ELISA kit Solute Carrier Family 1 Member 6 ELISA kit SLC1A6 ELISA kit EAAT4 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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