产品详情
简单介绍:
Anti-BCAS2 antibody (1-225) (STJ26653)
详情介绍:
Host: | Rabbit |
Applications: | WB/IHC/IF |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-BCAS2 (1-225) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000 IHC-P 1:50-1:200 IF/ICC 1:50-1:200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | BCAS2 |
Gene ID: | 10286 |
Uniprot ID: | SPF27_HUMAN |
Immunogen Region: | 1-225 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-225 of human BCAS2 (NP_005863.1). |
Immunogen Sequence: | MAGTGLVAGEVVVDALPYFD QGYEAPGVREAAAALVEEET RRYRPTKNYLSYLTAPDYSA FETDIMRNEFERLAARQPIE LLSMKRYELPAPSSGQKNDI TAWQECVNNSMAQLEHQAVR IENLELMSQHGCNAWKVYNE NLVHMIEHAQKELQKLRKHI QDLNWQRKNMQLTAGSKLRE MESNWVSLVSKNYEIERTIV QLENEIYQIKQQHGEANKEN IRQDF |
Tissue Specificity | Ubiquitously expressed. |
Function | Required for pre-mRNA splicing as component of the activated spliceosome. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR). |
Protein Name | Pre-Mrna-Splicing Factor Spf27 Breast Carcinoma-Amplified Sequence 2 Dna Amplified In Mammary Carcinoma 1 Protein Spliceosome-Associated Protein Spf 27 |
Database Links | Reactome: R-HSA-72163 |
Cellular Localisation | Nucleus Nucleolus |
Alternative Antibody Names | Anti-Pre-Mrna-Splicing Factor Spf27 antibody Anti-Breast Carcinoma-Amplified Sequence 2 antibody Anti-Dna Amplified In Mammary Carcinoma 1 Protein antibody Anti-Spliceosome-Associated Protein Spf 27 antibody Anti-BCAS2 antibody Anti-DAM1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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