产品详情
简单介绍:
Anti-ADCY3 antibody (950-1030 aa) (STJ191725)
详情介绍:
Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Rat/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Adenylate cyclase type 3 (950-1030 aa) is suitable for use in Western Blot and ELISA research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000 ELISA 1:5000-20000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | ADCY3 |
Gene ID: | 109 |
Uniprot ID: | ADCY3_HUMAN |
Immunogen Region: | 950-1030 aa |
Specificity: | ADCY3 Polyclonal Antibody detects endogenous levels of protein. |
Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 950-1030 |
Post Translational Modifications | Sumoylated. Sumoylation is required for targeting ot olfactory cilia. N-glycosylated. Rapidly phosphorylated after stimulation by odorants or forskolin. Phosphorylation by CaMK2 at Ser-1076 down-regulates enzyme activity. |
Function | Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Participates in signaling cascades triggered by odorant receptors via its function in cAMP biosynthesis. Required for the perception of odorants. Required for normal sperm motility and normal male fertility. Plays a role in regulating insulin levels and body fat accumulation in response to a high fat diet. |
Protein Name | Adenylate Cyclase Type 3 Atp Pyrophosphate-Lyase 3 Adenylate Cyclase Type Iii Ac-Iii Adenylate Cyclase - Olfactive Type Adenylyl Cyclase 3 Ac3 |
Database Links | Reactome: R-HSA-163359 Reactome: R-HSA-163615 Reactome: R-HSA-164378 Reactome: R-HSA-170660 Reactome: R-HSA-170670 Reactome: R-HSA-381753 Reactome: R-HSA-418555 Reactome: R-HSA-418594 Reactome: R-HSA-418597 Reactome: R-HSA-432040 Reactome: R-HSA-5610787 Reactome: R-HSA-9634597 Reactome: R-HSA-9660821 Reactome: R-HSA-9664323 |
Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein Cytoplasm Cell Projection Cilium Golgi Apparatus Also Detected In The Cytoplasm Close To Lipid Droplets |
Alternative Antibody Names | Anti-Adenylate Cyclase Type 3 antibody Anti-Atp Pyrophosphate-Lyase 3 antibody Anti-Adenylate Cyclase Type Iii antibody Anti-Ac-Iii antibody Anti-Adenylate Cyclase - Olfactive Type antibody Anti-Adenylyl Cyclase 3 antibody Anti-Ac3 antibody Anti-ADCY3 antibody Anti-KIAA0511 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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