产品详情
简单介绍:
Human P-Selectin/CD62P protein (Recombinant) (C-His-Avi) {Biotin} (STJP001544)
详情介绍:
Host: | HEK293 |
Note: | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Human P-Selectin/CD62P-C-His-Avi protein was developed from hek293 and has a target region of C-His-Avi. For use in research applications. |
Conjugation: | Biotin |
Formulation: | Lyophilised from 0.2 µm filtered PBS solution pH7.4. |
Dilution Range: | Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20sec, 5K RPM |
Storage Instruction: | The lyophilized protein is stable for at least 1 year from date of receipt at-20°C. |
Endotoxin: | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). |
Gene Symbol: | SELP |
Gene ID: | 6403 |
Uniprot ID: | LYAM3_HUMAN |
Immunogen Region: | Trp42-Ala771 |
Immunogen: | DNA sequence encoding Human P-Selectin/CD62P including a C-His-Avi tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology. |
Function | Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with SELPLG. |
Protein Name | P-Selectin Cd62 Antigen-Like Family Member P Granule Membrane Protein 140 Gmp-140 Leukocyte-Endothelial Cell Adhesion Molecule 3 Lecam3 Platelet Activation Dependent Granule-External Membrane Protein Padgem Cd Antigen Cd62p |
Database Links | Reactome: R-HSA-114608 Reactome: R-HSA-202733 |
Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein |
Alternative Protein Names | P-Selectin protein Cd62 Antigen-Like Family Member P protein Granule Membrane Protein 140 protein Gmp-140 protein Leukocyte-Endothelial Cell Adhesion Molecule 3 protein Lecam3 protein Platelet Activation Dependent Granule-External Membrane Protein protein Padgem protein Cd Antigen Cd62p protein SELP protein GMRP protein GRMP protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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