产品详情
简单介绍:
Human CHRDL1 (Chordin Like Protein 1) Sandwich ELISA Kit Ready-To-Use (STJE0014308)
详情介绍:
Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.054ng/mL |
Detection Limit: | 0.156-10ng/mL |
Short Description: | This CHRDL1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 3 hrs |
Gene Symbol: | CHRDL1 |
Gene ID: | 91851 |
Uniprot ID: | CRDL1_HUMAN |
Immunogen Region: | Ready-To-Use |
Sample Type: | tissue homogenates, cell lysates or other biological fluids. |
Tissue Specificity | Expressed in the developing cornea and in the eye anterior segment in addition to the retina. Differentially expressed in the fetal brain. There is high expression in cerebellum and neocortex. Expressed in retinal pericytes. |
Post Translational Modifications | |
Function | Antagonizes the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation. May play a role in embryonic bone formation. May also play an important role in regulating retinal angiogenesis through modulation of BMP4 actions in endothelial cells. Plays a role during anterior segment eye development. |
Protein Name | Chordin-Like Protein 1 Neuralin-1 Neurogenesin-1 Ventroptin |
Database Links | Reactome: R-HSA-201451 Reactome: R-HSA-381426 Reactome: R-HSA-8957275 |
Cellular Localisation | Secreted |
Alternative ELISA Names | Chordin-Like Protein 1 ELISA kit Neuralin-1 ELISA kit Neurogenesin-1 ELISA kit Ventroptin ELISA kit CHRDL1 ELISA kit NRLN1 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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