产品详情
简单介绍:
Mouse MFG-E8 protein (Recombinant) (C-His) (STJP001485)
详情介绍:
Host: | HEK293 cells |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Mouse MFG-E8-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
Formulation: | Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
Gene Symbol: | Mfge8 |
Gene ID: | 17304 |
Uniprot ID: | MFGM_MOUSE |
Immunogen: | Recombinant Mouse MFG-E8 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala23-Cys463) of mouse MFGE8/BA46 (Accession #NM_008594.2) fused with a 6×His tag at the C-terminus. |
Post Translational Modifications | N-glycosylated. Isoform 1 also exists in both an O-glycosylated and a non-O-glycosylated form. |
Function | Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization. |
Protein Name | Lactadherin Mfgm Milk Fat Globule-Egf Factor 8 Mfg-E8 Sed1 Sperm Surface Protein Sp47 Mp47 |
Database Links | Reactome: R-MMU-381426 Reactome: -MMU-8957275 |
Cellular Localisation | Membrane Peripheral Membrane Protein Secreted Cytoplasmic Vesicle Secretory Vesicle Acrosome Membrane Located In The Acrosomal Region Of Zona-Pellucida Bound Sperm |
Alternative Protein Names | Lactadherin protein Mfgm protein Milk Fat Globule-Egf Factor 8 protein Mfg-E8 protein Sed1 protein Sperm Surface Protein Sp47 protein Mp47 protein Mfge8 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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