产品详情
查看大图

  • 产品名称：Mouse SR-BI protein (Recombinant) (STJP000626)

  • 产品型号：STJP000626
  • 产品厂商：ST john's laboratory
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
Mouse SR-BI protein (Recombinant) (STJP000626)
详情介绍：
Host: HEK293
Note: STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Mouse SR-BI-protein was developed from hek293. For use in research applications.
Conjugation: Unconjugated
Formulation: Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose.
Storage Instruction: Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA
Endotoxin: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA
Gene Symbol: Scarb1
Gene ID: 20778
Uniprot ID: SCRB1_MOUSE
Immunogen Region: ECD
Immunogen: Optimized DNA sequence encoding I extracellular domain of Mouse Scavenger Receptor Class B Type I (SR-BI) including a C-terminal His tag was expressed in HEK293 cells. NA
Tissue Specificity Expressed primarily in liver, ovary and adrenal gland, and, at lower levels in other non-placental steroidogenic tissues, including adipose tissue, mammary gland and testis (at protein level). Isoform 2 is expressed at lower levels than isoform 1 in liver, testis and adrenal gland. At the mRNA, but not at the protein level, isoform 2 is the predominant isoform in testis (80%).
Post Translational Modifications N-glycosylated. The six cysteines of the extracellular domain are all involved in intramolecular disulfide bonds.
Function Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Both isoform 1 and isoform 2 act as receptors for HDL, mediating selective uptake of cholesteryl ether and HDL-dependent cholesterol efflux. Also facilitates the flux of free and esterified cholesterol between the cell surface and apoB-containing lipoproteins and modified lipoproteins, although less efficiently than HDL. May be involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity.
Protein Name Scavenger Receptor Class B Member 1
Srb1
Sr-Bi
Database Links Reactome: R-MMU-3000471
Reactome: -MMU-8964011
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Membrane
Caveola
Predominantly Localized To Cholesterol And Sphingomyelin-Enriched Domains Within The Plasma Membrane
Called Caveolae
Isoform 1: Cell Membrane
Isoform 2: Cell Membrane
Alternative Protein Names Scavenger Receptor Class B Member 1 protein
Srb1 protein
Sr-Bi protein
Scarb1 protein
Srb1 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
姓名：
电话：
您的需求：
 

沪公网安备 31011002002624号