产品详情
简单介绍:
Human CSF2Rb (Colony Stimulating Factor 2 Receptor Beta) Sandwich ELISA Kit Ready-To-Use (STJE0014558)
详情介绍:
Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.061ng/mL |
Detection Limit: | 0.156-10ng/mL |
Short Description: | This CSF2Rb Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 3 hrs |
Gene Symbol: | CSF2RB |
Gene ID: | 1439 |
Uniprot ID: | IL3RB_HUMAN |
Immunogen Region: | Ready-To-Use |
Sample Type: | tissue homogenates, cell lysates or other biological fluids. |
Tissue Specificity | |
Post Translational Modifications | May be phosphorylated by LYN. |
Function | Cell surface receptor that plays a role in immune response and controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells. Acts by forming an heterodimeric receptor through interaction with different partners such as IL3RA, IL5RA or CSF2RA. In turn, participates in various signaling pathways including interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor/CSF2 pathways. In unstimulated conditions, interacts constitutively with JAK1 and ligand binding leads to JAK1 stimulation and subsequent activation of the JAK-STAT pathway. |
Protein Name | Cytokine Receptor Common Subunit Beta Cdw131 Gm-Csf/Il-3/Il-5 Receptor Common Beta Subunit Cd Antigen Cd131 |
Database Links | Reactome: R-HSA-512988 Reactome: R-HSA-5673001 Reactome: R-HSA-5683826 Reactome: R-HSA-5688849 Reactome: R-HSA-5688890 Reactome: R-HSA-912526 |
Cellular Localisation | Membrane Single-Pass Type I Membrane Protein |
Alternative ELISA Names | Cytokine Receptor Common Subunit Beta ELISA kit Cdw131 ELISA kit Gm-Csf/Il-3/Il-5 Receptor Common Beta Subunit ELISA kit Cd Antigen Cd131 ELISA kit CSF2RB ELISA kit IL3RB ELISA kit IL5RB ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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