产品详情
简单介绍:
TLR13 Blocking Peptide for STJ503294 peptide (STJ505011)
详情介绍:
Applications: | Immunodepletion/Immunocompetition |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | TLR13 Blocking Peptide for STJ503294 is synthetically produced from the 400-480 sequence and is suitable for use in western blot applications. |
Formulation: | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: | Tlr13 |
Gene ID: | 279572 |
Uniprot ID: | TLR13_MOUSE |
Immunogen Region: | 400-480 |
Specificity: | This blocking peptide is recommended for use in combination with TLR13 antibody, STJ503294 |
Immunogen: | Synthetic peptide taken within amino acid region 400-480 of mouse TLR13 protein. |
Function | Component of innate and adaptive immunity that recognizes and binds 23S rRNA from bacteria. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Specifically binds the 5'-CGGAAAGACC-3' sequence on bacterial 23S rRNA, a sequence also bound by MLS group antibiotics (including erythromycin). May also recognize vesicular stomatitis virus.however, these data require additional evidences. |
Peptide Name | Toll-Like Receptor 13 |
Cellular Localisation | Endosome Membrane Single-Pass Type I Membrane Protein |
Alternative Peptide Names | Toll-Like Receptor 13 protein Tlr13 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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