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  • 产品名称：Human ERLIN2 (ER Lipid Raft Associated Protein 2) Sandwich ELISA Kit (STJE0008702)

  • 产品型号：STJE0008702
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human ERLIN2 (ER Lipid Raft Associated Protein 2) Sandwich ELISA Kit (STJE0008702)
详情介绍：
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.115ng/mL
Detection Limit: 0.312-20ng/mL
Short Description: This ERLIN2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: ERLIN2
Gene ID: 11160
Uniprot ID: ERLN2_HUMAN
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Ubiquitous.
Post Translational Modifications
Function Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs) such as ITPR1. Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex. Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. May promote ER retention of the SCAP-SREBF complex.
Protein Name Erlin-2
Endoplasmic Reticulum Lipid Raft-Associated Protein 2
Stomatin-Prohibitin-Flotillin-Hflc/K Domain-Containing Protein 2
Spfh Domain-Containing Protein 2
Database Links Reactome: R-HSA-382556
Reactome: R-HSA-5655302
Reactome: R-HSA-5678895
Reactome: R-HSA-8853336
Cellular Localisation Endoplasmic Reticulum Membrane
Single-Pass Type Ii Membrane Protein
Associated With Lipid Raft-Like Domains Of The Endoplasmic Reticulum Membrane
Alternative ELISA Names Erlin-2 ELISA kit
Endoplasmic Reticulum Lipid Raft-Associated Protein 2 ELISA kit
Stomatin-Prohibitin-Flotillin-Hflc/K Domain-Containing Protein 2 ELISA kit
Spfh Domain-Containing Protein 2 ELISA kit
ERLIN2 ELISA kit
C8orf2 ELISA kit
SPFH2 ELISA kit
UNQ2441 ELISA kit
PRO5003 ELISA kit
PRO9924 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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