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  • 产品名称：Anti-BCO2 antibody (170-410) (STJ27039)

  • 产品型号：STJ27039
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-BCO2 antibody (170-410) (STJ27039)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-BCO2 (170-410) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: BCO2
Gene ID: 83875
Uniprot ID: BCDO2_HUMAN
Immunogen Region: 170-410
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 170-410 of human BCO2 (NP_001243327.1).
Immunogen Sequence: KAAGFSYKVIRVPPEKVDLG ETIHGVQVICSIASTEKGKP SYYHSFGMTRNYIIFIEQPL KMNLWKIATSKIRGKAFSDG ISWEPQCNTRFHVVEKRTGQ LLPGRYYSKPFVTFHQINAF EDQGCVIIDLCCQDNGRTLE VYQLQNLRKAGEGLDQVHNS AAKSFPRRFVLPLNVSLNAP EGDNLSPLSYTSASAVKQAD GTIWCSHENLHQEDLEKEGG IEFPQIYYDRFSGKKYHFF
Tissue Specificity Highly expressed in retinal pigment epithelium. Also expressed in stomach, small intestine, liver, testis, kidney, adrenal gland, pancreas, heart, skeletal muscle and prostate (at protein level).
Function Broad specificity mitochondrial dioxygenase that mediates the asymmetric oxidative cleavage of carotenoids. Cleaves carotenes (pure hydrocarbon carotenoids) such as all-trans-beta-carotene and lycopene as well as xanthophylls (oxygenated carotenoids) such as zeaxanthin, lutein and beta-cryptoxanthin at both the 9,10 and the 9',10' carbon-carbon double bond. Through its function in carotenoids metabolism regulates oxidative stress and the production of important signaling molecules.
Protein Name Carotenoid-Cleaving Dioxygenase - Mitochondrial
B-Diox-Ii
Beta -Beta-Carotene 9' -10'-Oxygenase
Beta-Carotene Dioxygenase 2
Database Links Reactome: R-HSA-975634
Cellular Localisation Mitochondrion
Alternative Antibody Names Anti-Carotenoid-Cleaving Dioxygenase - Mitochondrial antibody
Anti-B-Diox-Ii antibody
Anti-Beta -Beta-Carotene 9' -10'-Oxygenase antibody
Anti-Beta-Carotene Dioxygenase 2 antibody
Anti-BCO2 antibody
Anti-BCDO2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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