产品详情
简单介绍:
Anti-ARAP3 antibody (C-Term) (STJ70429)
详情介绍:
Host: | Goat |
Applications: | Pep-ELISA/WB/IP |
Reactivity: | Human/Mouse/Dog/Pig/Cow |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Goat polyclonal antibody anti-ARAP3 (C-Term) is suitable for use in ELISA, Western Blot and Immunoprecipitation research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: | 0.5 mg/mL |
Dilution Range: | ELISA-antibody detection limit dilution 1:4000. |
Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: | ARAP3 |
Gene ID: | 64411 |
Uniprot ID: | ARAP3_HUMAN |
Immunogen Region: | C-Term |
Accession Number: | NP_071926.4 |
Immunogen Sequence: | CTSSPPSSQPLT |
Function | Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. Acts on ARF6, RAC1, RHOA and CDC42. Plays a role in the internalization of anthrax toxin. |
Protein Name | Arf-Gap With Rho-Gap Domain - Ank Repeat And Ph Domain-Containing Protein 3 Centaurin-Delta-3 Cnt-D3 |
Database Links | Reactome: R-HSA-8980692 Reactome: R-HSA-9013148 Reactome: R-HSA-9013149 Reactome: R-HSA-9013423 |
Cellular Localisation | Cytoplasm Cytoskeleton Cell Membrane Peripheral Membrane Protein Cell Projection Lamellipodium Ruffle Cytoplasmic And Associated With F-Actin-Rich Membrane Ruffles And Lamellipodia |
Alternative Antibody Names | Anti-Arf-Gap With Rho-Gap Domain - Ank Repeat And Ph Domain-Containing Protein 3 antibody Anti-Centaurin-Delta-3 antibody Anti-Cnt-D3 antibody Anti-ARAP3 antibody Anti-CENTD3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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