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  • 产品名称：Anti-AREB6/ZEB1 antibody (Internal) (STJ71831)

  • 产品型号：STJ71831-100
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-AREB6/ZEB1 antibody (Internal) (STJ71831)
详情介绍：
Host: Goat
Applications: Pep-ELISA/WB/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-AREB6/ZEB1 (Internal) is suitable for use in ELISA, Western Blot and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: WB-0.05-0.2µg/ml
ELISA-antibody detection limit dilution 1:32000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: ZEB1
Gene ID: 6935
Uniprot ID: ZEB1_HUMAN
Immunogen Region: Internal
Accession Number: NP_001121600.1; NP_110378.3
Specificity: This antibody is expected to recognize both reported isoforms (NP_001121600.1; NP_110378.3).
Immunogen Sequence: RPQIRQKIENKPLQE
Function Acts as a transcriptional repressor. Inhibits interleukin-2 (IL-2) gene expression. Enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and on the cell type. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1. Positively regulates neuronal differentiation. Represses RCOR1 transcription activation during neurogenesis. Represses transcription by binding to the E box (5'-CANNTG-3'). In the absence of TGFB1, acts as a repressor of COL1A2 transcription via binding to the E-box in the upstream enhancer region.
Protein Name Zinc Finger E-Box-Binding Homeobox 1
Nil-2-A Zinc Finger Protein
Negative Regulator Of Il2
Transcription Factor 8
Tcf-8
Database Links Reactome: R-HSA-6785807
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Zinc Finger E-Box-Binding Homeobox 1 antibody
Anti-Nil-2-A Zinc Finger Protein antibody
Anti-Negative Regulator Of Il2 antibody
Anti-Transcription Factor 8 antibody
Anti-Tcf-8 antibody
Anti-ZEB1 antibody
Anti-AREB6 antibody
Anti-TCF8 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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