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  • 产品名称：Anti-Beta-2 microglobulin antibody [EBS-O-109] (STJ16101034)

  • 产品型号：STJ16101034
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-Beta-2 microglobulin antibody [EBS-O-109] (STJ16101034)
详情介绍：
Host: Mouse
Applications: ELISA/FC/IHC
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Beta-2 microglobulin is suitable for use in ELISA, Flow Cytometry and Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: EBS-O-109
Conjugation: Unconjugated
Isotype: IgG2ak
Formulation: PBS with 0.02% Sodium Azide.
Purification: Affinity purified from tissue culture.
Concentration: Can be provided as 100 µg/mL, 500 µg/mL or 1mg/mL.
Dilution Range: ELISA (solid phase: 0, 1-100 µg/ml; tracer: 0, 001-100 µg/ml for 30 min at RT). Flow cytometry (0, 5-1, 0 µg/million cells in 0, 1 ml). Immunohistology (1-2 µg/ml for 30-60 minutes at RT; information on a suitable antigen retrieval method for stainin
Storage Instruction: Store for up to 1 year at 2-8°C upon receipt.
Gene Symbol: B2M
Gene ID: 567
Uniprot ID: B2MG_HUMAN
Immunogen: A BALB/c mouse was immunized with human PBL from a T-ALL patient. Fusion partner: NS-1.
Post Translational Modifications Glycation of Ile-21 is observed in long-term hemodialysis patients.
Function Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation.
Protein Name Beta-2-Microglobulin Cleaved Into - Beta-2-Microglobulin Form Pi 5.3
Database Links Reactome: R-HSA-1236974
Reactome: R-HSA-1236977
Reactome: R-HSA-164940
Reactome: R-HSA-198933
Reactome: R-HSA-2172127
Reactome: R-HSA-2424491
Reactome: R-HSA-6798695
Reactome: R-HSA-877300
Reactome: R-HSA-9637628
Reactome: R-HSA-9705671
Reactome: R-HSA-977225
Reactome: R-HSA-983170
Cellular Localisation Secreted
Cell Surface
Detected In Serum And Urine
(Microbial Infection) In The Presence Of M
Tuberculosis Esxa-Esxb Complex Decreased Amounts Of B2m Are Found On The Cell Surface
Alternative Antibody Names Anti-Beta-2-Microglobulin Cleaved Into - Beta-2-Microglobulin Form Pi 5.3 antibody
Anti-B2M antibody
Anti-CDABP0092 antibody
Anti-HDCMA22P antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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