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  • 产品名称：Human FFAR1 (Free Fatty Acid Receptor 1) Sandwich ELISA Kit Ready-To-Use (STJE0015223)

  • 产品型号：STJE0015223
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human FFAR1 (Free Fatty Acid Receptor 1) Sandwich ELISA Kit Ready-To-Use (STJE0015223)
详情介绍：
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.54ng/mL
Detection Limit: 1.56-100ng/mL
Short Description: This FFAR1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: FFAR1
Gene ID: 2864
Uniprot ID: FFAR1_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity Detected in brain and pancreas. Detected in pancreatic beta cells.
Post Translational Modifications
Function G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. Fatty acid binding increases glucose-stimulated insulin secretion, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1). May also play a role in bone homeostasis.receptor signaling activates pathways that inhibit osteoclast differentiation. Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, leading to an increase of the intracellular calcium concentration. Seems to act through a G(q) and G(i)-mediated pathway. Mediates the anti-inflammatory effects of omega-3 polyunsaturated fatty acids (PUFAs) via inhibition of NLRP3 inflammasome activation.
Protein Name Free Fatty Acid Receptor 1
G-Protein Coupled Receptor 40
Database Links Reactome: R-HSA-381771
Reactome: R-HSA-400511
Reactome: R-HSA-416476
Reactome: R-HSA-434316
Reactome: R-HSA-444209
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative ELISA Names Free Fatty Acid Receptor 1 ELISA kit
G-Protein Coupled Receptor 40 ELISA kit
FFAR1 ELISA kit
GPR40 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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