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  • 产品名称：Anti-BMPR2 antibody (739-1038) (STJ118671)

  • 产品型号：STJ118671
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-BMPR2 antibody (739-1038) (STJ118671)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-BMPR2 (739-1038) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:200-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: BMPR2
Gene ID: 659
Uniprot ID: BMPR2_HUMAN
Immunogen Region: 739-1038
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 739-1038 of human BMPR2 (NP_001195.2).
Immunogen Sequence: PTQIYPLPKQQNLPKRPTSL PLNTKNSTKEPRLKFGSKHK SNLKQVETGVAKMNTINAAE PHVVTVTMNGVAGRNHSVNS HAATTQYANGTVLSGQTTNI VTHRAQEMLQNQFIGEDTRL NINSSPDEHEPLLRREQQAG HDEGVLDRLVDRRERPLEGG RTNSNNNNSNPCSEQDVLAQ GVPSTAADPGPSKPRRAQRP NSLDLSATNVLDGSSIQIGE STQDGKSGSGEKIKKRVKT
Tissue Specificity Highly expressed in heart and liver.
Function On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6.
Protein Name Bone Morphogenetic Protein Receptor Type-2
Bmp Type-2 Receptor
Bmpr-2
Bone Morphogenetic Protein Receptor Type Ii
Bmp Type Ii Receptor
Bmpr-Ii
Database Links Reactome: R-HSA-201451
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Bone Morphogenetic Protein Receptor Type-2 antibody
Anti-Bmp Type-2 Receptor antibody
Anti-Bmpr-2 antibody
Anti-Bone Morphogenetic Protein Receptor Type Ii antibody
Anti-Bmp Type Ii Receptor antibody
Anti-Bmpr-Ii antibody
Anti-BMPR2 antibody
Anti-PPH1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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