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  • 产品名称：Anti-BNIP3L antibody (STJ192181)

  • 产品型号：STJ192181
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-BNIP3L antibody (STJ192181)
详情介绍：
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
ELISA 1:5000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: BNIP3L
Gene ID: 665
Uniprot ID: BNI3L_HUMAN
Specificity: BNI3L Polyclonal Antibody detects endogenous levels of protein.
Immunogen: Synthesized peptide derived from part of the human protein
Function Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates in mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. May function as a tumor suppressor.
Protein Name Bcl2/Adenovirus E1b 19 Kda Protein-Interacting Protein 3-Like
Adenovirus E1b19k-Binding Protein B5
Bcl2/Adenovirus E1b 19 Kda Protein-Interacting Protein 3a
Nip3-Like Protein X
Nip3l
Database Links Reactome: R-HSA-6803204
Cellular Localisation Nucleus Envelope
Endoplasmic Reticulum
Mitochondrion Outer Membrane
Membrane
Single-Pass Membrane Protein
Colocalizes With Spata18 At The Mitochondrion Outer Membrane
Alternative Antibody Names Anti-Bcl2/Adenovirus E1b 19 Kda Protein-Interacting Protein 3-Like antibody
Anti-Adenovirus E1b19k-Binding Protein B5 antibody
Anti-Bcl2/Adenovirus E1b 19 Kda Protein-Interacting Protein 3a antibody
Anti-Nip3-Like Protein X antibody
Anti-Nip3l antibody
Anti-BNIP3L antibody
Anti-BNIP3A antibody
Anti-BNIP3H antibody
Anti-NIX antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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