产品详情
简单介绍:
Human FceRII (Receptor II For The Fc Region Of Immunoglobulin E) Sandwich ELISA Kit Ready-To-Use (STJE0015203)
详情介绍:
Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.107ng/mL |
Detection Limit: | 0.312-20ng/mL |
Short Description: | This FceRII Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 3 hrs |
Gene Symbol: | FCER2 |
Gene ID: | 2208 |
Uniprot ID: | FCER2_HUMAN |
Immunogen Region: | Ready-To-Use |
Sample Type: | serum, plasma or other biological fluids. |
Tissue Specificity | |
Post Translational Modifications | N- and O-glycosylated. The secreted form sCD23 is produced by ADAM10-mediated ectodomain shedding. |
Function | Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B cells. On B cells, initiates IgE-dependent antigen uptake and presentation to T cells. On macrophages, upon IgE binding and antigen cross-linking induces intracellular killing of parasites through activation of L-Arginine-nitric oxide pathway. |
Protein Name | Low Affinity Immunoglobulin Epsilon Fc Receptor Blast-2 C-Type Lectin Domain Family 4 Member J Fc-Epsilon-Rii Immunoglobulin E-Binding Factor Lymphocyte Ige Receptor Cd Antigen Cd23 Cleaved Into - Low Affinity Immunoglobulin Epsilon Fc Receptor Membrane-Bound Form - Low Affinity Immunoglobulin Epsilon Fc Receptor Soluble Form |
Database Links | Reactome: R-HSA-2197563 Reactome: R-HSA-6783783 Reactome: R-HSA-6785807 |
Cellular Localisation | Cell Membrane Single-Pass Type Ii Membrane Protein Lipid-Anchor Secreted Also Exists As A Soluble Excreted Form Scd23 |
Alternative ELISA Names | Low Affinity Immunoglobulin Epsilon Fc Receptor ELISA kit Blast-2 ELISA kit C-Type Lectin Domain Family 4 Member J ELISA kit Fc-Epsilon-Rii ELISA kit Immunoglobulin E-Binding Factor ELISA kit Lymphocyte Ige Receptor ELISA kit Cd Antigen Cd23 Cleaved Into - Low Affinity Immunoglobulin Epsilon Fc Receptor Membrane-Bound Form - Low Affinity Immunoglobulin Epsilon Fc Receptor Soluble Form ELISA kit FCER2 ELISA kit CD23A ELISA kit CLEC4J ELISA kit FCE2 ELISA kit IGEBF ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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